PUSH THE ENVELOPE.
JOIN OUR TEAM.
We follow the science that will lead us to the best possible outcomes for patients.
We are focused on delivering cures and transforming the lives of patients with devastating liver disorders, utilizing new advancements in genetic medicine.
Our experienced team is passionate about the work we do harnessing the power of cutting-edge in vivo gene insertion technology to transform the lives of patients and families living with devastating disorders caused by inborn errors of metabolism.
Pronounced “ee-ah-cure,” our name is inspired by the Latin word iecur, which means liver—the organ where many critical metabolic pathways occur. iECURE’s investigational therapies are designed to address diseases caused by inborn errors of metabolism that originate in the liver. Our pipeline includes programs targeting these disorders, with one now in clinical trials.
Our science is at the leading edge, and so are we. Our team of experts is here to transform lives and bring potentially curative treatments to patients in need. Great work takes a deep level of collaboration at all levels, and we strive every day to foster an environment that inspires innovation, execution and an unrelenting commitment to patients.
Courage
means boldly embracing challenges, taking smart risks, and pushing scientific boundaries in pursuit of transformative therapies for rare diseases. We face uncertainty with resilience, learn from setbacks, and move forward with the inner strength needed to break new ground.
Accountability
means owning our words, actions, and outcomes—delivering on our commitments to each other and to the patients we serve. We hold ourselves to the highest standards as responsible stewards of our mission, demonstrating integrity and responsibility through the decisions we make every day.
Perseverance
means advancing our mission with unwavering commitment and a mindset focused on achieving the best possible outcomes. We create our own opportunities through preparation, problem-solving, and attention to detail—and we work with integrity and tenacity to deliver exceptional results in the relentless pursuit of our goals.
Agility
means staying focused on our mission while adapting quickly to change. We challenge the status quo with open minds and creative thinking, making fast, informed decisions to navigate the complexities of rare disease drug development and drive innovative solutions forward.
Interested in joining our team of genetic medicine experts?
Please email careers@iecure.com to learn more, and browse our current job openings below.
No current openings.
Director, Project Management Operations
The Director of Project Management will lead development and execution of planning for strategic, operational, and clinical development initiatives within a dynamic biotech environment. Reporting to the Senior Vice President of Operations, this role requires a purpose-driven leader with strong project management expertise, cross-functional collaboration skills, and the ability to shape company culture and values. The successful candidate will serve as a brand ambassador and contribute to the execution of high-priority clinical programs with a potential for transformative clinical outcomes for rare disease communities.
Characteristics sought for a good cultural fit to the company include the ability to work collaboratively, strong project management skills, excellent planning and budgeting skills, ability to think strategically and act independently, a “hands on” approach in the implementation of an agreed-upon plan, nimble problem-solving skills, an innate sense of urgency, creative thinking about what is possible in execution, and general positivity.
Project Management Operations
July 2025
Fulltime, based in Blue Bell, PA
iECURE is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.
Director, Global Regulatory Affairs
Reporting directly to the VP of Regulatory Affairs (RA), the Director of RA will be responsible for providing US and global regulatory leadership in support of the development, registration, and life-cycle management of our innovative gene therapy programs.
The responsibilities include providing US and global regulatory leadership and direction for gene therapy products, including developing long and short-term planning of regulatory projects that align with the company’s business plan, and developing strategies to ensure effective achievement of regulatory/business objectives. The individual will be responsible for staying current in the regulatory environment and assessing and communicating the impact of changes on business and product development.
The Director of RA will be an experienced and highly motivated professional who has developed regulatory strategy associated with all phases of drug development, including the coordination and preparation of document packages for regulatory submissions and leading cross functional teams. This individual will have a strong rapport and collaborative relationship with the US Food and Drug Administration (FDA) and other regulatory agencies worldwide.
Characteristics sought for a good cultural fit to the company include the ability to work collaboratively, strong project management skills, excellent planning and budgeting skills, ability to think strategically and act independently, a “hands on” approach in the implementation of an agreed-upon plan, nimble problem-solving skills, an innate sense of urgency, creative thinking about what is possible in execution, and general positivity.
Regulatory Affairs
March 2025
Fulltime (5 days per week), Office-Based Position in Blue Bell, PA
iECURE is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.